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KMID : 0385019890050010047
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Korean Journal of Laboratory Animal Science
1989 Volume.5 No. 1 p.47 ~ p.57
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A Pathologic Observation on Spontaneous Lung Tumors in the Mice
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Abstract
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A total of 470 ICR and BALB/c mice were evaluated for spontaneous lung tumors. Each neoplasms was graded for age, size, histological type and degree of differentiation grossly and microscopically. The results were as follows;
1. The incidence of mice with lung tumors was 3, 4% in totally which is consisted of 2 cases in 6∼9 months old, 11 in 9∼12 months old and 3 in over 12 months old.
2. Most of the tumors were small in size measuring below 0. 5㎜.
3. Histopathologically, the tumors were classified as papillary, solid or mixed in type. The papillary type was prominent mostly.
4. Most of the tumors were shown well differentiated while the tumors of larger size(over 1.0㎜) and older age hover 12 months) were frequently shown poorly differentiated.
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